This case was referred by a field vet.
Canine
pyometra is defined as a chronic purulent post estrum endometritis,
with or without polysystemic effects. False/pseudo pregnancy, or pseudocyesis,
is a normal physiologic process that occurs in female dogs which may or may not
be associated with reproductive organ disorders which is
seen 45-60 days after a normal estrous (heat) period when progesterone levels,
which rise after ovulation, begin to fall .
The progressive degenerative process in the development of cystic endometrial
hyperplasia is usually proposed as the initiating lesion for pyometra in
bitches; this is mediated by progesterone and potentially aggravated by
estrogens. CEH is also associated with
mucometra; it results from endometrial thickening with the accumulation of
viscid uterine fluid caused by hyperplastic and hypertrophic endometrial
glands. CEH is not associated with clinical signs unless the uterine content
becomes infected; this is referred to as pyometra
Progesterone influence hyperplasia of the
endometrium and endometrial glands, decreasing myometrial contractions and
inhibiting local leukocyte response to infection. Clinically
pseudo pregnant dogs had diffuse thickening of the uterus and additionally,
macroscopically visible swellings that corresponded to 2cm diameter regions of
pronounced endometrial hyperplasia. THIS CASE HAD 3 LITRES OF PUS IN A UTERUS WHICH WAS 7 TIMES BIGGER THAN ITS NORMAL SIZE.
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