CLINICAL VETERINARY SURGERY VIDEOS - CYSTIC ENDOMETRITIS PYOMETRA COMPLEX IN A GREAT DANE BITCH

CYSTIC ENDOMETRITIS - PYOMETRA COMPLEX IN A GREAT DANE BITCH .
This case was referred by a field vet.

Canine pyometra is defined as a chronic purulent post estrum endometritis, with or without polysystemic effects. False/pseudo pregnancy, or pseudocyesis, is a normal physiologic process that occurs in female dogs which may or may not be  associated with reproductive organ  disorders which is seen 45-60 days after a normal estrous (heat) period when progesterone levels, which rise after ovulation, begin to fall . The progressive degenerative process in the development of cystic endometrial hyperplasia is usually proposed as the initiating lesion for pyometra in bitches; this is mediated by progesterone and potentially aggravated by estrogens. CEH is also associated with mucometra; it results from endometrial thickening with the accumulation of viscid uterine fluid caused by hyperplastic and hypertrophic endometrial glands. CEH is not associated with clinical signs unless the uterine content becomes infected; this is referred to as pyometra 

Progesterone  influence hyperplasia of the endometrium and endometrial glands, decreasing myometrial contractions and inhibiting  local leukocyte response to infection. Clinically pseudo pregnant dogs had diffuse thickening of the uterus and additionally, macroscopically visible swellings that corresponded to 2cm diameter regions of pronounced endometrial hyperplasia. THIS CASE HAD 3 LITRES OF PUS IN A UTERUS WHICH WAS 7 TIMES BIGGER THAN ITS NORMAL SIZE.